Gene

cdknx

Species
Xenopus tropicalis
Symbol
cdknx
Name
cyclin-dependent kinase inhibitor xic1
Synonyms
  • cdknx
  • cyclin-dependent kinase inhibitor xic1
Biotype
gene
Automated Description
Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in negative regulation of epithelial cell proliferation and negative regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be located in nucleus. Is expressed in ectoderm; mesoderm; musculoskeletal system; nervous system; and visual system. Human ortholog(s) of this gene implicated in several diseases, including Beckwith-Wiedemann syndrome; IMAGe syndrome; hematologic cancer (multiple); hyperinsulinism; and multiple endocrine neoplasia type 4. Orthologous to several human genes including CDKN1C (cyclin dependent kinase inhibitor 1C).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
109.4885M109.4890M109.4895M109.4900M109.4905M109.4910M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions