Predicted to enable channel activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in several cellular components, including Golgi apparatus; apical plasma membrane; and basolateral plasma membrane. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus and nephrogenic diabetes insipidus type 2. Orthologous to human AQP2 (aquaporin 2).