Gene

acvr1

Species
Xenopus tropicalis
Symbol
acvr1
Name
activin A receptor type 1
Synonyms
  • activin A receptor type 1
  • actri
Biotype
gene
Automated Description
Predicted to enable SMAD binding activity and transforming growth factor beta receptor activity, type I. Predicted to be involved in several processes, including dorsal/ventral pattern formation; heart development; and transforming growth factor beta receptor superfamily signaling pathway. Predicted to act upstream of or within cell surface receptor protein serine/threonine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of BMP receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in exfoliation syndrome; fibrodysplasia ossificans progressiva; primary angle-closure glaucoma; and primary open angle glaucoma. Orthologous to human ACVR1 (activin A receptor type 1).
XBXT Description
activin receptor, serine/threonine protein kinase
https://www.xenbase.org/gene/showgene.do?method=display&geneId=478849
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
68.82M68.83M68.84M68.85M68.86M68.87M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions