Gene

tap2

Species
Xenopus tropicalis
Symbol
tap2
Name
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms
  • abc18
  • abcb3
Biotype
gene
Automated Description
Predicted to enable ABC-type oligopeptide transporter activity. Predicted to act upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class I and transmembrane transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of TAP complex. Human ortholog(s) of this gene implicated in several diseases, including aspirin-induced respiratory disease; autoimmune disease (multiple); cervical cancer (multiple); dengue hemorrhagic fever; and systemic scleroderma (multiple). Orthologous to human TAP2 (transporter 2, ATP binding cassette subfamily B member).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
51.562M51.564M51.566M51.568M51.570M51.572M51.574M51.576M51.578M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions