Gene

pdx1

Species
Xenopus tropicalis
Symbol
pdx1
Name
pancreatic and duodenal homeobox 1
Synonyms
  • ipf1
  • pancreatic and duodenal homeobox 1
Biotype
gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and type B pancreatic cell differentiation. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in endoderm. Human ortholog(s) of this gene implicated in cerebral infarction; hyperglycemia; maturity-onset diabetes of the young type 4; pancreatic agenesis 1; and type 2 diabetes mellitus. Orthologous to human PDX1 (pancreatic and duodenal homeobox 1).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
152.174M152.176M152.178M152.180M152.182M152.184M152.186M152.188M152.190M152.192M152.194M152.196M152.198M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions