Gene

meis2

Species
Xenopus tropicalis
Symbol
meis2
Name
Meis homeobox 2
Synonyms
  • LOC108699226
  • Meis homeobox 2
Biotype
gene
Automated Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in several processes, including embryonic pattern specification; eye development; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within animal organ development and regulation of DNA-templated transcription. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in cleft palate; cleft palate, cardiac defects, and intellectual disabillity; learning disability; open-angle glaucoma; and orofacial cleft. Orthologous to human MEIS2 (Meis homeobox 2).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMEIS25 of 9YesYes   
Mus musculusMeis25 of 9YesYes   
Rattus norvegicusMeis25 of 9YesYes   
Xenopus laevismeis2.L1 of 1YesYes           
Danio reriomeis2a5 of 9YesYes   
Danio reriomeis2b3 of 9NoYes   
Drosophila melanogasterhth5 of 9YesNo   
Caenorhabditis elegansunc-624 of 9YesNo   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
meis1140385794 of 8  
meis3238281754 of 8  
pknox2341352394 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
90.87M90.88M90.89M90.90M90.91M90.92M90.93M90.94M90.95M90.96MNM_001097218.1 (meis2)XM_012967801.2 (meis2)XM_012967802.2 (meis2)XM_012967803.2 (meis2)XM_012967804.2 (meis2)XM_012967805.2 (meis2)XM_012967806.2 (meis2)

Sequence Details

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Expression

Primary Sources
Other Sources
None
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available