Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ERAD pathway and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of Derlin-1 retrotranslocation complex. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human RNF139 (ring finger protein 139).