Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); endocrine gland cancer (multiple); lung carcinoma (multiple); neurodegenerative disease (multiple); and senile cataract. Orthologous to human ATM (ATM serine/threonine kinase).