Gene

atm.L

Species
Xenopus laevis
Symbol
atm.L
Name
ATM serine/threonine kinase
Synonyms
  • at1
  • atdc
Biotype
gene
Automated Description
Predicted to enable 1-phosphatidylinositol-3-kinase activity and protein serine/threonine kinase activity. Predicted to act upstream of or within mitotic spindle assembly checkpoint signaling and response to ionizing radiation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); endocrine gland cancer (multiple); lung carcinoma (multiple); neurodegenerative disease (multiple); and senile cataract. Orthologous to human ATM (ATM serine/threonine kinase).
XBXL Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XL9.2
Viewer Help
1.34M1.35M1.36M1.37M1.38M1.39M1.40M1.41M1.42M1.43M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions