Gene

lrrk2

Species
Xenopus tropicalis
Symbol
lrrk2
Name
leucine-rich repeat kinase 2
Synonyms
  • leucine-rich repeat kinase 2
  • lrrk2
Biotype
gene
Automated Description
Predicted to enable protein serine/threonine kinase activity and purine ribonucleoside triphosphate binding activity. Predicted to act upstream of or within cell communication and regulation of signal transduction. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in Crohn's disease; Parkinson's disease; Parkinson's disease 8; Parkinsonism; and cancer. Orthologous to human LRRK2 (leucine rich repeat kinase 2).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensLRRK29 of 9YesYes   
Mus musculusLrrk29 of 9YesYes   
Rattus norvegicusLrrk29 of 9YesYes   
Xenopus laevislrrk2.L1 of 1YesYes           
Danio reriolrrk29 of 9YesYes   
Drosophila melanogasterLrrk3 of 9YesYes   
Caenorhabditis eleganslrk-12 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
65.85M65.86M65.87M65.88M65.89M65.90M65.91M65.92M65.93M65.94MXM_002932204.4 (lrrk2)XM_012959985.2 (lrrk2)XM_012959986.2 (lrrk2)XM_012959987.2 (lrrk2)XM_012959988.2 (lrrk2)XM_018092315.1 (lrrk2)XT-9_1-rna81 (lrrk2)XR_001924208.1 (LOC108646165)

Sequence Details

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Expression

Primary Sources
Other Sources
None
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available