Predicted to enable intracellularly calcium-gated chloride channel activity. Predicted to act upstream of or within chloride transport and proteolysis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to several human genes including CLCA1 (chloride channel accessory 1) and CLCA4 (chloride channel accessory 4).