Gene

sting1

Species
Xenopus tropicalis
Symbol
sting1
Name
stimulator of interferon response cGAMP interactor 1
Synonyms
  • stimulator of interferon response cGAMP interactor 1
  • sting1
Biotype
gene
Automated Description
Predicted to enable 2',3'-cyclic GMP-AMP binding activity and cyclic-di-GMP binding activity. Predicted to be involved in several processes, including defense response to symbiont; macroautophagy; and positive regulation of metabolic process. Predicted to be located in autophagosome membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; and perinuclear region of cytoplasm. Predicted to be active in autophagosome and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            Genome location
            Assembly version
            XT9.1
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            17.374M17.376M17.378M17.380M17.382M17.384M17.386M17.388M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            None
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            sting1 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              sting1 role
              sting1 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
              Reference
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