Gene

plcb1

Species
Xenopus tropicalis
Symbol
plcb1
Name
phospholipase C beta 1
Synonyms
  • LOC108716400
  • phospholipase C beta 1
Biotype
gene
Automated Description
Predicted to enable calmodulin binding activity and phosphatidylinositol phospholipase C activity. Predicted to be involved in several processes, including memory; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Predicted to act upstream of or within intracellular signal transduction and lipid catabolic process. Predicted to be active in cytoplasm and nuclear speck. Human ortholog(s) of this gene implicated in Alzheimer's disease; developmental and epileptic encephalopathy 12; and myelodysplastic syndrome. Orthologous to human PLCB1 (phospholipase C beta 1).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
21.75M21.80M21.85M21.90M21.95M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions