Gene

aqp2.S

Species
Xenopus laevis
Symbol
aqp2.S
Name
aquaporin 2
Synonyms
  • aqp-CD
  • aqp2.S
Biotype
gene
Automated Description
Predicted to enable channel activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in several cellular components, including Golgi apparatus; apical plasma membrane; and basolateral plasma membrane. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus and nephrogenic diabetes insipidus type 2. Orthologous to human AQP2 (aquaporin 2).
XBXL Description
integral membrane pore (water channel) protein
https://www.xenbase.org/gene/showgene.do?method=display&geneId=481400
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensAQP21 of 1YesYes           
Xenopus tropicalisaqp21 of 1YesYes           
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
all annotationsall disease by infectious agentbacterial infectious diseasefungal infectious diseaseparasitic infectious diseaseviral infectious diseaseall disease of anatomical entitycardiovascular system diseasecentral nervous system diseaseendocrine system diseasegastrointestinal system diseasehematopoietic system diseaseimmune system diseaseintegumentary system diseasemusculoskeletal system diseaseperipheral nervous system diseasereproductive system diseaserespiratory system diseasesensory system diseasethoracic diseaseurinary system diseaseall disease of cellular proliferationbenign neoplasmcancerpre-malignant neoplasmall genetic diseasechromosomal diseasemonogenic diseasepolygenic diseaseall other diseasedisease of mental healthdisease of metabolismphysical disordersyndrome
aqp2.S (Xla)
AQP2 (Hsa)
aqp2 (Xtr)
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
Homo sapiensAQP2
is marker fordiabetic ketoacidosis
  • IEP
    Homo sapiensAQP2
    is implicated innephrogenic diabetes insipidus
    • IDA
    • IAGP
    • IMP
      Homo sapiensAQP2
      is implicated innephrogenic diabetes insipidus type 2
      • IAGP
        Showing 1 - 3 of 3 rows
        per page

        Transgenic Alleles

        No data available

        Models

        No data available

        Sequence Feature Viewer

        Genome location
        Assembly version
        XL9.2
        Viewer Help
        130.989M130.990M130.991M130.992M130.993M130.994M130.995M130.996M130.997MNM_001085862.1 (aqp2.S)XL-9_2-rna14591 (aqp2.S)

        Sequence Details

        Transcript: Mode:

        Expression

        Primary Sources
        Other Sources
        None
        all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
        aqp2.S (Xla)
        Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

        Molecular Interactions

        No data available

        Genetic Interactions

        No data available