Gene

fbn1

Species
Xenopus tropicalis
Symbol
fbn1
Name
fibrillin 1
Synonyms
  • fbn1
  • fibrillin
Biotype
gene
Automated Description
Predicted to enable calcium ion binding activity. Predicted to be located in extracellular region and microfibril. Human ortholog(s) of this gene implicated in several diseases, including CREST syndrome; Weill-Marchesani syndrome; aortic disease (multiple); autosomal dominant isolated ectopia lentis 1; and bone disease (multiple). Orthologous to human FBN1 (fibrillin 1).
XBXT Description
Fibrillins and related proteins containing Ca2+-binding EGF-like domains
https://www.xenbase.org/gene/showgene.do?method=display&geneId=954189
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
93.86M93.88M93.90M93.92M93.94M93.96M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions