Gene

txnrd1

Species
Xenopus tropicalis
Symbol
txnrd1
Name
thioredoxin reductase 1
Synonyms
  • thioredoxin reductase 1
  • txnrd1
Biotype
gene
Automated Description
Predicted to enable flavin adenine dinucleotide binding activity and glutathione-disulfide reductase (NADPH) activity. Predicted to be involved in cell redox homeostasis; cellular response to oxidative stress; and glutathione metabolic process. Predicted to act upstream of or within response to oxidative stress. Predicted to be active in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human TXNRD1 (thioredoxin reductase 1).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensTXNRD15 of 9YesYes   
Mus musculusTxnrd15 of 9YesYes   
Rattus norvegicusTxnrd15 of 9YesYes   
Xenopus laevistxnrd1.L1 of 1YesYes           
Xenopus laevistxnrd1.S1 of 1YesYes           
Caenorhabditis eleganstrxr-14 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
txnrd3159582694 of 8  
txnrd2249070563 of 8  
gsr350155372 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
40.385M40.390M40.395M40.400M40.405M40.410M40.415M

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
None
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available