Predicted to enable IMP dehydrogenase activity. Predicted to be involved in GTP biosynthetic process. Predicted to act upstream of or within GMP biosynthetic process. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1).