Predicted to enable double-stranded DNA binding activity. Predicted to be involved in mitotic sister chromatid cohesion. Predicted to act upstream of or within cell division and chromosome organization. Predicted to be located in chromosome and nucleus. Predicted to be part of mitotic cohesin complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3; hepatocellular carcinoma; and intellectual disability. Orthologous to human SMC3 (structural maintenance of chromosomes 3).
XBXT Description
Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3)