Gene

tfam

Species
Xenopus tropicalis
Symbol
tfam
Name
transcription factor A, mitochondrial
Synonyms
  • mttf1
  • mttfa
Biotype
gene
Automated Description
Predicted to enable DNA binding activity, bending and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and transcription initiation at mitochondrial promoter. Predicted to be located in mitochondrial nucleoid and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; amyotrophic lateral sclerosis; and mitochondrial DNA depletion syndrome 15. Orthologous to human TFAM (transcription factor A, mitochondrial).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensTFAM5 of 9YesYes   
Mus musculusTfam5 of 9YesYes   
Rattus norvegicusTfam5 of 9YesYes   
Xenopus laevistfam.L1 of 1YesYes           
Xenopus laevistfam.S1 of 1YesYes           
Danio reriotfam5 of 9YesYes   
Drosophila melanogasterTFAM4 of 9YesYes   
Caenorhabditis eleganshmg-54 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
7.394M7.395M7.396M7.397M7.398M7.399M7.400M7.401MXM_002937102.4 (tfam)XT-9_1-rna4470 (tfam)

Sequence Details

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Expression

Primary Sources
Other Sources
None
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available