Version: 8.0.0Date: Tue Jan 28 2025
Gene
dld
- Species
- Xenopus tropicalis
- Symbol
- dld
- Name
- dihydrolipoamide dehydrogenase
- Synonyms
- dihydrolipoamide dehydrogenase
- dld
- Biotype
- gene
- Automated Description
- Predicted to enable dihydrolipoyl dehydrogenase activity and flavin adenine dinucleotide binding activity. Predicted to be involved in 2-oxoglutarate metabolic process and pyruvate metabolic process. Predicted to be located in acrosomal vesicle and motile cilium. Predicted to be part of oxoglutarate dehydrogenase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human DLD (dihydrolipoamide dehydrogenase).
- XBXT Description
- Dihydrolipoamide dehydrogenasehttps://www.xenbase.org/gene/showgene.do?method=display&geneId=982850
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- Not Available
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | DLD | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
| Mus musculus | Dld | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
| Rattus norvegicus | Dld | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
| Xenopus laevis | dld.S | 1 of 1 | Yes | Yes | ☑ |
| Xenopus laevis | dld.L | 1 of 1 | Yes | Yes | ☑ |
| Danio rerio | dldh | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
| Caenorhabditis elegans | dld-1 | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
| Saccharomyces cerevisiae | LPD1 | 4 of 9 | Yes | Yes | ☐ ☐☐☑☑☐☑☑☐ |
| Saccharomyces cerevisiae | IRC15 | 3 of 9 | No | Yes | ☑ ☐☐☐☐☐☑☑☐ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Paralogy
| Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
|---|---|---|---|---|---|---|
| nsun4 | 1 | 80 | 45 | 31 | 2 of 8 | ☐ ☑☐☑☐☐☐☐ |
Disease Associations
Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|---|
| No records match query. Try removing filters. | ||||||||
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Sequence Feature Viewer
- Genome location
- Chr03:66426084...66444568 - (18.48 kb)
- Assembly version
- XT9.1
- Viewer Help
Data currently unavailable; sequence viewer under construction