Gene

setd2

Species
Xenopus tropicalis
Symbol
setd2
Name
SET domain containing 2
Synonyms
  • SET domain containing 2
  • setd2
Biotype
gene
Automated Description
Predicted to enable histone H3K36 methyltransferase activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within chromatin organization; methylation; and regulation of DNA-templated transcription. Predicted to be active in chromosome and nucleus. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder; clear cell renal cell carcinoma; gastrointestinal system cancer (multiple); lung disease (multiple); and malignant mesothelioma (multiple). Orthologous to human SETD2 (SET domain containing 2, histone lysine methyltransferase).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
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Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions