Contributes to proton transmembrane transporter activity. Acts upstream of or within several processes, including caudal fin development; fin regeneration; and notochord cell vacuolation. Predicted to be part of proton-transporting two-sector ATPase complex, catalytic domain. Is expressed in several structures, including digestive system; eye; gonad; heart; and unfertilized egg. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIC. Orthologous to several human genes including ATP6V1E1 (ATPase H+ transporting V1 subunit E1).