Version: 8.1.0
Date: Fri Apr 18 2025
cxadr
Danio rerioZFIN:ZDB-GENE-020814-2
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

cxadr

Species
Danio rerio
Symbol
cxadr
Name
CXADR Ig-like cell adhesion molecule
Synonyms
  • cb331
  • fb76g12
Biotype
protein coding gene
Automated Description
Enables virus receptor activity. Acts upstream of or within kidney development. Located in bicellular tight junction and cell surface. Is expressed in several structures, including digestive system; epithelium; heart; nervous system; and pronephros. Orthologous to human CXADR (CXADR Ig-like cell adhesion molecule).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR44468
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensCXADR10 of 10YesYes☑ ☑☑☑☑☑☑☑☑ ☑
Mus musculusCxadr10 of 10YesYes☑ ☑☑☑☑☑☑☑☑ ☑
Mus musculusGm11233 of 10NoYes☑ ☐☐☐☐☐☑☑☐ ☐
Rattus norvegicusCxadr9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicaliscxadr9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
vsig8b135555385 of 8☑ ☑☐☑☐☑☑☐ 
vsig8a233359405 of 8☑ ☑☐☑☐☑☑☐ 
igsf11344946313 of 8☑ ☑☐☐☐☐☑☐ 
esamb447541274 of 8☑ ☑☐☑☐☐☑☐ 
esama544644284 of 8☑ ☑☐☑☐☐☑☐ 
gpa33a634644284 of 8☑ ☑☐☑☐☐☑☐ 
zgc:165604729151314 of 8☑ ☑☐☑☐☐☑☐ 
jam2a835238233 of 8☑ ☑☐☐☐☐☑☐ 
f11r.1932240243 of 8☑ ☑☐☐☐☐☑☐ 
gpa33b1029248282 of 8☐ ☐☐☑☐☐☑☐ 
jam2b1132338253 of 8☑ ☑☐☐☐☐☑☐ 
jam3b1231441243 of 8☑ ☑☐☐☐☐☑☐ 
jam3a1330240243 of 8☑ ☑☐☐☐☐☑☐ 
si:dkey-22i16.91436434202 of 8☑ ☐☐☐☐☐☑☐ 
f11r.21523937243 of 8☑ ☑☐☐☐☐☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
alkaline phosphatase activity decreased occurrence, abnormal
cloacal chamber deformed, abnormal
gut epithelium plasma membrane increased distance gut epithelium plasma membrane, abnormal
gut epithelium structure, abnormal
heart edematous, abnormal
podocyte morphology, abnormal
post-vent region curvature, abnormal
pronephric glomerulus morphology, abnormal
pronephric tubule brush border epithelial cell disorganized, abnormal
pronephric tubule epithelium structure, abnormal
Showing 1 - 10 of 15 rows
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
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    Alleles and Variants

    Genome location
    Assembly version
    GRCz11
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    la017483Tg
    • la017483
    		allele
    la027163Tg
    • la027163
    		allele
    sa31783allele with one associated variant
    point mutation
    • splice donor variant
    Showing 1 - 3 of 3 rows
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    View detailed Alleles/Variants information
    Download all Alleles/Variants for all genes of the species

    Transgenic Alleles

    No data available

    Models

    Model name
    Experimental condition
    Associated Human Diseases
    Associated Phenotypes
    Modifier
    Source
    AB + MO1-cxadr
    has condition:
    standard conditions
    • cloacal chamber deformed, abnormal
    • heart edematous, abnormal
    		ZFIN
    AB + MO2-cxadr
    has condition:
    standard conditions
    • alkaline phosphatase activity decreased occurrence, abnormal
    • cloacal chamber deformed, abnormal
    		ZFIN
    Showing 1 - 2 of 2 rows
    per page

    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCz11
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available