Gene

vkorc1

Species
Danio rerio
Symbol
vkorc1
Name
vitamin K epoxide reductase complex, subunit 1
Synonyms
  • fc03a11
  • si:dkey-32n7.10
Biotype
protein coding gene
Automated Description
Predicted to enable vitamin-K-epoxide reductase (warfarin-sensitive) activity. Predicted to be involved in blood coagulation and vitamin K metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including head; liver; muscle; pleuroperitoneal region; and vertebra. Human ortholog(s) of this gene implicated in combined deficiency of vitamin K-dependent clotting factors 2 and warfarin resistance. Orthologous to human VKORC1 (vitamin K epoxide reductase complex subunit 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14519
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
4.2175M4.2180M4.2185M4.2190M4.2195M4.2200M4.2205M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions