Enables monoatomic ion channel activity and phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity. Acts upstream of or within phosphatidylinositol dephosphorylation and regulation of endocytosis. Predicted to be located in membrane. Predicted to be active in cytosol. Is expressed in blood vessel; gill; pleuroperitoneal region; and ventral mesoderm. Orthologous to human TPTE (transmembrane phosphatase with tensin homology) and TPTE2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2).