Version: 8.0.0Date: Tue Jan 28 2025
Gene
dspb
- Species
- Danio rerio
- Symbol
- dspb
- Name
- desmoplakin b
- Synonyms
- fi04e12
- wu:fb77d08
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable structural molecule activity. Involved in desmosome organization; establishment of skin barrier; and heart development. Acts upstream of or within camera-type eye development; fin regeneration; and heart contraction. Predicted to be located in cytoskeleton; desmosome; and membrane. Predicted to be active in cytoplasm; intercalated disc; and plasma membrane. Predicted to colocalize with intermediate filament. Is expressed in several structures, including epidermis; head; heart; otic vesicle; and solid lens vesicle. Human ortholog(s) of this gene implicated in Carvajal syndrome; arrhythmogenic right ventricular cardiomyopathy; arrhythmogenic right ventricular dysplasia 8; dilated cardiomyopathy; and keratosis palmoplantaris striata 2. Orthologous to human DSP (desmoplakin).
- ZFIN Description
- Not Available
- Cross References
- Additional Information
- Literature
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume