protein tyrosine phosphatase non-receptor type 11a
Synonyms
fa14b09
ptpn11
Biotype
protein coding gene
Automated Description
Enables protein tyrosine phosphatase activity. Acts upstream of or within several processes, including embryonic morphogenesis; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and neuromast hair cell development. Predicted to be active in cytoplasm. Is expressed in several structures, including blastoderm; blastomere; gill; immune system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 1; atrophic gastritis; juvenile myelomonocytic leukemia; and metachondromatosis. Orthologous to human PTPN11 (protein tyrosine phosphatase non-receptor type 11).