Version: 8.0.0Date: Tue Jan 28 2025
Gene
ptmaa
- Species
- Danio rerio
- Symbol
- ptmaa
- Name
- prothymosin alpha a
- Synonyms
- cb515
- fk58d04
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable histone binding activity. Predicted to be involved in negative regulation of apoptotic process and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including Leydig cell; corpuscles of Stannius; digestive system; nervous system; and pleuroperitoneal region. Orthologous to human PTMA (prothymosin alpha).
- ZFIN Description
- Not Available
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR22745
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | PTMA | 9 of 10 | Yes | Yes | ☐ ☑☑☑☑☑☑☑☑ ☑ |
| Mus musculus | Ptma | 8 of 10 | Yes | Yes | ☐ ☑☑☑☑☑☑☐☑ ☑ |
| Rattus norvegicus | Ptmal5 | 7 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☐☑ |
| Rattus norvegicus | Ptmal3 | 7 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☐☑ |
| Rattus norvegicus | Ptma | 7 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☐☑ |
| Xenopus tropicalis | ptma | 2 of 9 | Yes | Yes | ☐ ☐☐☑☐☐☑☐☐ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Paralogy
| Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
|---|---|---|---|---|---|---|
| ptmab | 1 | 112 | 76 | 62 | 4 of 8 | ☐ ☐☑☑☐☑☑☐ |
| si:ch211-222l21.1 | 2 | 118 | 62 | 47 | 3 of 8 | ☐ ☐☐☑☐☑☑☐ |
Disease Associations
Cases where the expected disease association was NOT found
| all annotations | all disease by infectious agent | bacterial infectious disease | fungal infectious disease | parasitic infectious disease | viral infectious disease | all disease of anatomical entity | cardiovascular system disease | central nervous system disease | endocrine system disease | gastrointestinal system disease | hematopoietic system disease | immune system disease | integumentary system disease | musculoskeletal system disease | peripheral nervous system disease | reproductive system disease | respiratory system disease | sensory system disease | thoracic disease | urinary system disease | all disease of cellular proliferation | benign neoplasm | cancer | pre-malignant neoplasm | all genetic disease | chromosomal disease | monogenic disease | polygenic disease | all other disease | disease of mental health | disease of metabolism | physical disorder | syndrome | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ptmaa (Dre) |
Cell color indicative of annotation volume
No data available
Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
| Danio rerio | tku2Tg |
|
Showing 1 - 1 of 1 rows
per page
Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
|---|---|---|---|---|---|
| AB/EKW + MO1-ptmaa + MO4-bbs4 |
|
| ZFIN |
Showing 1 - 1 of 1 rows
per page
Sequence Feature Viewer
- Genome location
- Chr6:29791164...29795029 (3.87 kb)
- Assembly version
- GRCz11
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- Other Sources
| all annotations | all anatomical structures | alimentary part of gastrointestinal system | chemosensory system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | mechanosensory system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | sensory system | vestibulo-auditory system | visual system | endoderm | ectoderm | mesoderm | mesenchyme | adipose tissue | appendage | entire extraembryonic component | imaginal precursor | pharyngeal arch | other | all stages | embryo stage | post embryonic, pre-adult | post-juvenile adult stage | all cellular components | extracellular region | plasma membrane | synapse | cell junction | cell projection | cytoplasmic vesicle | endosome | vacuole | golgi apparatus | endoplasmic reticulum | cytosol | mitochondrion | nucleus | chromosome | cytoskeleton | protein-containing complex | other locations | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ptmaa (Dre) |
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.