signal transducer and activator of transcription 6, interleukin-4 induced
Synonyms
sb:eu508
wu:fj66g07
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within granuloma formation and innate immune response. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including digestive system; hematopoietic system; integument; kidney; and telencephalon. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lipoid nephrosis; prostate carcinoma; rectum adenocarcinoma; and urinary schistosomiasis. Orthologous to human STAT6 (signal transducer and activator of transcription 6).