Version: 8.0.0
Date: Tue Jan 28 2025
anxa4
Danio rerioZFIN:ZDB-GENE-030707-1
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

anxa4

Species
Danio rerio
Symbol
anxa4
Name
annexin A4
Synonyms
None
Biotype
protein coding gene
Automated Description
Predicted to enable calcium-dependent phospholipid binding activity and phosphatidylserine binding activity. Predicted to be located in zymogen granule membrane. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in several structures, including digestive system; endoderm; hatching gland; mesenchymal cell; and pronephric duct. Orthologous to human ANXA4 (annexin A4).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10502
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Must provide at least one subject
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
        s870Tg + MO1-anxa4
        has condition:
        standard conditions
        • liver apoptotic process increased process quality, abnormal
        		ZFIN
        s870Tg + MO2-anxa4
        has condition:
        standard conditions
        • liver apoptotic process increased process quality, abnormal
        		ZFIN
        WT + CRISPR2-anxa4
        has condition:
        standard conditions
        • liver apoptotic process increased process quality, abnormal
        		ZFIN
        s870Tg + CRISPR2-anxa4ZFIN
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        Sequence Feature Viewer

        Genome location
        Assembly version
        GRCz11
        Viewer Help
        Data currently unavailable; sequence viewer under construction

        Sequence Details

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        Expression

        Primary Sources
        Other Sources
        Must provide at least one subject
        Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

        Molecular Interactions

        anxa4 molecule type
        Interactor gene
        Interactor species
        Interactor molecule type
        Detection methods
        Source
        Reference
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          Genetic Interactions

          anxa4 role
          anxa4 genetic perturbation
          Interactor gene
          Interactor species
          Interactor role
          Interactor genetic perturbation
          Interaction type
          Phenotype or trait
          Source
          Reference
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