Gene

traf4b

Species
Danio rerio
Symbol
traf4b
Name
tnf receptor-associated factor 4b
Synonyms
  • traf4
Biotype
protein coding gene
Automated Description
Predicted to enable signaling adaptor activity. Predicted to be involved in cell surface receptor signaling pathway and regulation of canonical NF-kappaB signal transduction. Predicted to act upstream of or within several processes, including activation of NF-kappaB-inducing kinase activity; positive regulation of JNK cascade; and protein ubiquitination. Predicted to be active in cytoplasm. Orthologous to human TRAF4 (TNF receptor associated factor 4).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10131
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensTRAF44 of 10YesNo  
Mus musculusTraf44 of 10YesNo  
Rattus norvegicusTraf43 of 9YesNo   
Xenopus tropicalistraf43 of 9YesNo   
Drosophila melanogasterTraf48 of 10YesNo  
Caenorhabditis eleganstrf-14 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
traf4a148284727 of 8  
traf2b258740274 of 8  
traf2a358842273 of 8  
traf3459539263 of 8  
traf6551244264 of 8  
traf5654543282 of 8  
traf1755442233 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
GRCz11
Viewer Help
39.006M39.008M39.010M39.012M39.014M39.016M39.018M39.020M39.022M39.024M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
sa13894allele with one associated variant
point mutation
  • stop gained
sa24012allele with one associated variant
point mutation
  • splice donor variant
Showing 1 - 2 of 2 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
39.006M39.008M39.010M39.012M39.014M39.016M39.018M39.020M39.022M39.024Mtraf4b-201 (traf4b)

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available