Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within intrahepatic bile duct development. Predicted to be active in nucleus. Is expressed in several structures, including digestive system; nervous system; presumptive neural retina; pronephric duct; and trigeminal placode. Orthologous to human ONECUT1 (one cut homeobox 1).