Gene

dnaaf4

Species
Danio rerio
Symbol
dnaaf4
Name
dynein axonemal assembly factor 4
Synonyms
  • dyx1c1
  • zgc:77853
Biotype
protein coding gene
Automated Description
Predicted to enable nuclear estrogen receptor binding activity. Acts upstream of or within cilium assembly; epithelial cilium movement involved in determination of left/right asymmetry; and left/right axis specification. Predicted to be located in dynein axonemal particle; neuron projection; and nucleus. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; nervous system; neural tube; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in dyslexia and primary ciliary dyskinesia 25. Orthologous to human DNAAF4 (dynein axonemal assembly factor 4).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22904

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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    Alleles and Variants

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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
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        Models

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          Sequence Feature Viewer

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          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          dnaaf4 molecule type
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            Genetic Interactions

            dnaaf4 role
            dnaaf4 genetic perturbation
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