Gene

nf2b

Species
Danio rerio
Symbol
nf2b
Name
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor b
Synonyms
  • nf2
  • NF2a
Biotype
protein coding gene
Automated Description
Predicted to enable actin binding activity and integrin binding activity. Predicted to be involved in several processes, including positive regulation of early endosome to late endosome transport; positive regulation of protein localization to early endosome; and regulation of hippo signaling. Predicted to be located in cytoskeleton and membrane. Predicted to be active in several cellular components, including adherens junction; apical part of cell; and filopodium. Used to study choledochal cyst. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); malignant pleural mesothelioma; meningioma (multiple); neurilemmoma; and vestibular schwannomatosis. Orthologous to human NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23281
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
25.802M25.804M25.806M25.808M25.810M25.812M25.814M25.816M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions