Predicted to enable aspartic-type endopeptidase activity. Acts upstream of or within enteric nervous system development and melanocyte migration. Predicted to be located in membrane. Predicted to be active in endosome; plasma membrane; and trans-Golgi network. Is expressed in several structures, including intestinal bulb; neural crest; optic vesicle; polster; and retina. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human BACE2 (beta-secretase 2).