Gene

bace2

Species
Danio rerio
Symbol
bace2
Name
beta-secretase 2
Synonyms
  • bace2l
  • fi26d02
Biotype
protein coding gene
Automated Description
Predicted to enable aspartic-type endopeptidase activity. Acts upstream of or within enteric nervous system development and melanocyte migration. Predicted to be located in membrane. Predicted to be active in endosome; plasma membrane; and trans-Golgi network. Is expressed in several structures, including intestinal bulb; neural crest; optic vesicle; polster; and retina. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human BACE2 (beta-secretase 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13683
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
6.460M6.462M6.464M6.466M6.468M6.470M6.472M6.474M6.476M6.478M6.480M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions