piezo type mechanosensitive ion channel component 1 (Er blood group)
Synonyms
FAM38A
im:7149048
Biotype
protein coding gene
Automated Description
Enables mechanosensitive monoatomic ion channel activity and voltage-gated channel activity. Involved in regulation of epidermal cell division. Acts upstream of or within several processes, including cell volume homeostasis; epidermal cell division; and ventriculo bulbo valve development. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in nucleate erythrocyte; ventral mesoderm; and vertebral column. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema. Orthologous to human PIEZO1 (piezo type mechanosensitive ion channel component 1 (Er blood group)).