Gene

piezo1

Species
Danio rerio
Symbol
piezo1
Name
piezo type mechanosensitive ion channel component 1 (Er blood group)
Synonyms
  • FAM38A
  • im:7149048
Biotype
protein coding gene
Automated Description
Enables mechanosensitive monoatomic ion channel activity and voltage-gated channel activity. Involved in regulation of epidermal cell division. Acts upstream of or within several processes, including cell volume homeostasis; epidermal cell division; and ventriculo bulbo valve development. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in nucleate erythrocyte; ventral mesoderm; and vertebral column. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema. Orthologous to human PIEZO1 (piezo type mechanosensitive ion channel component 1 (Er blood group)).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13167

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

No data available

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions