Gene

lepb

Species
Danio rerio
Symbol
lepb
Name
leptin b
Synonyms
  • si:dkey-21o22.1
Biotype
protein coding gene
Automated Description
Predicted to enable hormone activity. Acts upstream of or within glucose homeostasis; regulation of primary metabolic process; and response to starvation. Predicted to be located in extracellular region. Is expressed in several structures, including digestive system; gill; heart; hypophysis; and pleuroperitoneal region. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; congenital leptin deficiency; liver disease (multiple); lung disease (multiple); and type 2 diabetes mellitus. Orthologous to human LEP (leptin).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11724
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
19.0318M19.0320M19.0322M19.0324M19.0326M19.0328M19.0330M19.0332M19.0334M19.0336M19.0338M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions