Gene

kif7

Species
Danio rerio
Symbol
kif7
Name
kinesin family member 7
Synonyms
  • cos2
  • costal2
Biotype
protein coding gene
Automated Description
Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Acts upstream of or within determination of left/right symmetry; negative regulation of smoothened signaling pathway; and photoreceptor cell outer segment organization. Located in cilium and cytoplasm. Part of Hedgehog signaling complex. Is expressed in head; myotome; neural tube; otic vesicle; and somite. Used to study idiopathic scoliosis. Human ortholog(s) of this gene implicated in acrocallosal syndrome; cleft lip; and hydrolethalus syndrome 2. Orthologous to human KIF7 (kinesin family member 7).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24115
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
14.395M14.400M14.405M14.410M14.415M14.420M14.425M14.430M14.435M14.440M14.445M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions