Predicted to enable type II interferon receptor binding activity. Acts upstream of or within defense response to Gram-negative bacterium and immune response. Predicted to be located in extracellular region. Is expressed in digestive system; gill; reproductive system; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in several diseases, including ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; factor VIII deficiency; and leukemia (multiple). Orthologous to human IFNG (interferon gamma).