Gene

f2r

Species
Danio rerio
Symbol
f2r
Name
coagulation factor II (thrombin) receptor
Synonyms
  • PAR1-5A
  • si:ch211-130m23.4
Biotype
protein coding gene
Automated Description
Enables thrombin-activated receptor activity. Acts upstream of or within circulatory system development; endothelial to hematopoietic transition; and negative regulation of hematopoietic stem cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; hematopoietic system; mesoderm; and pleuroperitoneal region. Orthologous to human F2R (coagulation factor II thrombin receptor).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24232
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
46.1962M46.1964M46.1966M46.1968M46.1970M46.1972M46.1974M46.1976M46.1978M46.1980M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions