Gene

top1a

Species
Danio rerio
Symbol
top1a
Name
DNA topoisomerase Ia
Synonyms
  • top1l
  • wu:fc66a02
Biotype
protein coding gene
Automated Description
Predicted to enable DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA replication; DNA topological change; and chromosome segregation. Predicted to act upstream of or within rhythmic process. Predicted to be located in chromosome and nucleus. Predicted to be active in nucleolus. Orthologous to human TOP1 (DNA topoisomerase I).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10290
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
25.298M25.300M25.302M25.304M25.306M25.308M25.310M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions