Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Involved in regulation of angiogenesis. Acts upstream of or within sprouting angiogenesis. Predicted to be part of cytosolic [4Fe-4S] assembly targeting complex. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Orthologous to human CIAO3 (cytosolic iron-sulfur assembly component 3).