Gene

ncf2

Species
Danio rerio
Symbol
ncf2
Name
neutrophil cytosolic factor 2
Synonyms
  • p67phox
  • zgc:158405
Biotype
protein coding gene
Automated Description
Predicted to enable superoxide-generating NADPH oxidase activator activity. Predicted to be involved in superoxide anion generation. Predicted to act upstream of or within phagocytosis and respiratory burst. Predicted to be part of NADPH oxidase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal recessive chronic granulomatous disease 2; and rheumatoid arthritis. Orthologous to human NCF2 (neutrophil cytosolic factor 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15175
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
41.330M41.331M41.332M41.333M41.334M41.335M41.336M41.337M41.338M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions