Predicted to enable cytokine binding activity and cytokine receptor activity. Involved in leptin-mediated signaling pathway and regulation of canonical Wnt signaling pathway. Acts upstream of or within several processes, including oocyte maturation; ovulation; and type B pancreatic cell development. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including digestive system; musculature system; nervous system; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); liver disease (multiple); obesity; obstructive sleep apnea; and type 2 diabetes mellitus. Orthologous to human LEPR (leptin receptor).