Version: 8.0.0
Date: Tue Jan 28 2025
xrcc2
Danio rerioZFIN:ZDB-GENE-121029-1
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

xrcc2

Species
Danio rerio
Symbol
xrcc2
Name
X-ray repair complementing defective repair in Chinese hamster cells 2
Synonyms
None
Biotype
protein coding gene
Automated Description
Predicted to enable ATP binding activity; ATP-dependent DNA damage sensor activity; and DNA binding activity. Predicted to act upstream of or within double-strand break repair via homologous recombination. Predicted to be located in replication fork. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group U; pancreatic cancer; primary ovarian insufficiency 17; and spermatogenic failure 50. Orthologous to human XRCC2 (X-ray repair cross complementing 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          No data available

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          xrcc2 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            xrcc2 role
            xrcc2 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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