Gene

tgfbr2b

Species
Danio rerio
Symbol
tgfbr2b
Name
transforming growth factor beta receptor 2b
Synonyms
  • cb537
  • TGF-beta receptor 2
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including activin binding activity; transforming growth factor beta binding activity; and transmembrane receptor protein serine/threonine kinase activity. Acts upstream of or within hematopoietic stem cell differentiation. Predicted to be located in membrane raft. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; head; mesoderm; and trigeminal ganglion. Human ortholog(s) of this gene implicated in several diseases, including Loeys-Dietz syndrome 2; Lynch syndrome (multiple); Marfan syndrome; gastrointestinal system cancer (multiple); and mismatch repair cancer syndrome. Orthologous to human TGFBR2 (transforming growth factor beta receptor 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
39.51M39.52M39.53M39.54M39.55M39.56M39.57M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions