Version: 8.0.0Date: Tue Jan 28 2025
Allele/Variant
Hsap\RUNX1::Hsap\RUNX1T1YTR.UAS.cSa
- Species
- Drosophila melanogaster
- Symbol
- Hsap\RUNX1::Hsap\RUNX1T1YTR.UAS.cSa
- Category
- allele
- Allele of gene
- None
- Transgenic Constructs
- Synonyms
- Hsap\RUNX1::Hsap\RUNX1T1[YTR.Scer\UAS.cSa]
- Hsap\RUNX1::Hsap\RUNX1T1[YTR.UAS.cSa]
- Description
- UAS regulatory sequences drive expression of a mutant form of Hsap\RUNX1::Hsap\RUNX1T1 in which DNA binding and CBFβ binding have been abrogated. The tyrosine at residue 113 and the threonine at residue 161 have been mutated to alanine, and the arginine at residue 174 has been mutated to glutamine.
- Additional Information
- Literature
Transgenic Constructs
This allele contains 1 transgenic construct- Symbol
- P{UAS-RUNX1-RUNX1T1.YTR}
- Expressed Components
- RUNX1::RUNX1T1
- Knock-down Targets
- None
- Regulatory Regions
- UAS