CG4743^I172G

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Species

Drosophila melanogaster

Symbol

CG4743^I172G

Category

allele

Allele of gene

CG4743

Transgenic Constructs

None

Synonyms

• CG4743[I172G]

Description

Re-integration of sequence using the attP site present in TI{TI}CG4743^KO (after first removing the loxP cassette), reconstituting a mutant CG4743 transcription unit at the native locus; contains a I172G amino acid substitution (this mutation is equivalent to a variant identified in the orthologous human SLC25A26 gene in a patient with severe mitochondrial disease). In addition, a loxP cassette containing a w^GMR.PHb marker has been inserted downstream of the CG4743 coding sequence and the attP site has been converted into an attR site (this is located upstream of the CG4743 coding sequence).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations