Hps5^ru2-J

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Species

Mus musculus

Symbol

Hps5^ru2-J

Category

allele

Allele of gene

Hps5

Transgenic Constructs

None

Synonyms

• ru-2^J
• ru-2J

Show All 4

Description

This spontaneous mutation was shown to be an allele of Hps^ru-2 by complementation testing, and thus an allele of Hps5^ru2. Subsequent sequence analysis identified the replacement of G with TT in codon 757, putatively resulting in a frameshift mutation that precludes the translation of 311 carboxy terminal amino acids. Northern blot analysis indicated that the mutation did not affect the expression pattern of the gene.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations