Ghrhr^lit

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Species

Mus musculus

Symbol

Ghrhr^lit

Category

allele

Allele of gene

Ghrhr

Transgenic Constructs

None

Synonyms

• lit
• lit^m

Description

The mutation in little mice is a A-to-G transition in codon 60 that alters this residue from a aspartate to a glycine in the encoded protein (p.D60G). Reduced levels of mRNA were noted in total RNA derived from pituitary of homozygous mice, and in vitro assays demonstrated that no functional protein is made from this allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations